Receptor, Serotonin, 5-HT1B |
| 5-HT(1B) Receptor; 5-HT(1Dbeta) Receptor; 5-HT1B Receptor; 5-HT1Dbeta Receptor; 5-Hydroxytryptamine 1B Receptor; 5-Hydroxytryptamine 1B Receptors; Receptor, 5-Hydroxytryptamine 1B; Receptor, Serotonin Type 1Dbeta; Serotonin 1D Beta Receptor |
| A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect. |
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