Receptor, erbB-3

Proto-Oncogene Protein c-erbB-3; Proto-Oncogene Proteins erbB-3; HER 3 Proto Oncogene Protein; Proto Oncogene Protein c erbB 3; Proto Oncogene Protein erbB 3; Proto Oncogene Proteins erbB 3; Proto-Oncogene Protein, HER-3; Receptor, erbB 3
A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF Receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) and the erbB-2 receptor (RECEPTOR, ERBB-2). Overexpression of the erbB-3 receptor is associated with tumorigenesis.