STAT3 Transcription Factor |
| APRF Transcription Factor; Acute-Phase Response Factor; IL6-Response Factor; LIF-Response Factor; STAT3 Protein; STAT3a Transcription Factor; STAT3b Transcription Factor; Signal Transducer and Activator of Transcription 3; Stat3alpha Transcription Factor |
| A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130. |
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