STAT5 Transcription Factor |
| Mammary Gland Factor; Mammary Gland-Specific Nuclear Factor; STAT5 Protein; STAT5a Protein; STAT5a Transcription Factor; STAT5alpha Protein; STAT5b Protein; STAT5b Transcription Factor; STAT5beta Protein |
| A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA. |
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