Serotonin Uptake Inhibitors

Inhibitors, 5-HT Uptake; Inhibitors, 5-Hydroxytryptamine Uptake; Inhibitors, Serotonin Reuptake; Inhibitors, Serotonin Uptake; Reuptake Inhibitors, Serotonin; Uptake Inhibitors, 5-HT; Uptake Inhibitors, 5-Hydroxytryptamine; Uptake Inhibitors, Serotonin
Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here.