Spleen Focus-Forming Viruses |
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| Focus-Forming Virus, Spleen; Focus-Forming Viruses, Spleen; Spleen Focus Forming Viruses; Spleen Focus-Forming Virus | |
| Strains of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with other viral types. | |