Steroid 11-beta-Hydroxylase |
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| 11 beta-Hydroxylase; CYP 11B1; Cytochrome P450 11B1; Steroid 11 Hydroxylase; Steroid 11-Hydroxylase; Steroid-11-Hydroxylase; 11 beta Hydroxylase; Cytochrome P 450 CYP11B1; Steroid 11 beta Hydroxylase; Steroid 11 beta Monooxygenase | |
| A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). | |