Steroid 21-Hydroxylase |
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| 21-Hydroxylase; Cytochrome P-450 21-Hydroxylase; Cytochrome P-450 c21; Cytochrome P-450(c-21); Cytochrome P450c21; Progesterone 21-Hydroxylase; Steroid-21-Hydroxylase; 21 Hydroxylase; Cytochrome P 450 21 Hydroxylase; Cytochrome P 450 CYP21 | |
| An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). | |