Succinate-Semialdehyde Dehydrogenase
NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase; Succinate Semialdehyde Dehydrogenase; Succinic Semialdehyde Dehydrogenase; Dehydrogenase, Succinate Semialdehyde; Dehydrogenase, Succinate-Semialdehyde; Dehydrogenase, Succinic Semialdehyde
An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).