Thymopoietins

TP-49; Thymopoietin I; Thymopoietin II; I, Thymopoietin; II, Thymopoietin; TP 49
Two closely related polypeptides (molecular weight 7,000) isolated from the thymus gland. These hormones induce the differentiation of prothymocytes to thymocytes within the thymus. They also cause a delayed impairment of neuromuscular transmission in vivo and are therefore believed to be the agent responsible for myasthenia gravis.