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Thyroxine
3,5,3',5'-Tetraiodothyronine; Abbot Brand of Levothyroxine Sodium; Allphar Brand of Levothyroxine Sodium; Aventis Brand of Levothyroxine Sodium; Berlin-Chemie Brand of Levothyroxine Sodium; Berlthyrox; Byk Brand of Levothyroxine Sodium
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.