Tissue Plasminogen Activator

Actilyse; Activase; Boehringer Ingelheim Brand of Alteplase; Genentech Brand of Alteplase; Hoffmann-La Roche Brand of Alteplase; Lysatec rt-PA; Promeco Brand of Alteplase; TTPA; Tissue Activator D-44; Activator, T-Plasminogen
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to PLASMIN. It has fibrin-binding activity and is immunologically different from URINARY PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases. EC 3.4.21.68.