Tumor Necrosis Factor-alpha |
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| Cachectin-Tumor Necrosis Factor; Tumor Necrosis Factor; Cachectin Tumor Necrosis Factor; Tumor Necrosis Factor alpha | |
| Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. | |