Uroporphyrinogen Decarboxylase |
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| Uroporphyrinogen III Decarboxylase; Carboxy-Lyase, Uroporphyrinogen; Decarboxylase, Uroporphyrinogen; Decarboxylase, Uroporphyrinogen III; Uroporphyrinogen Carboxy Lyase | |
| An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA. | |