Wiskott-Aldrich Syndrome Protein Family

WAS Protein Family, Member 1; WAS Protein Family, Member 2; WAS Protein Family, Member 3; WASF1 Protein; WASF2 Protein; WASF3 Protein; WASP Protein Family; WAVE1 Protein; WAVE2 Protein; WAVE3 Protein; Wiskott-Aldrich Syndrome Protein Family, Member 1
A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.